We drove down from New York to Florida using a car hired from this site without any problems. We picked up our car from JFK Airport where it was only a 30 minute drive to the I95 south. We spent a week driving down visiting the following places on the way:-

Lancaster County - we stayed on an Amish Farm and ate at a restaurant where we were the only non-Amish
Gettysburg - Very atmospheric and worth getting a CD for a tour of the battlefields
Sky Line Drive through the Blue Ridge Mountains - we stayed in a fantastic cabin but unfortunately the pass will probably be closed by snow in February
Williamsburg - we spent 2 nights with B&B in an old colonial style house
Charleston - beautiful old houses and well worth taking a horse and carriage ride. At Sham Creek there are several good fish restaurants where the trawlers bring in their catch

We pre-booked overnight stays at the Amish Farm, Blue Ridge Mountains and Williamsburg. We wished we had booked something in Charleston as we left it until late afternoon before looking for anything and ended up in a rather seedy looking area. Otherwise it was quite easy to find somewhere to stay.

Enjoy your trip

Mo