Depends on how long you are going for. For me I would always book everything myself we have been twice and flew into one airport and out of another. I would say some of the places to see should definitely be San Fran, Lake Tahoe, Yosemite, Las Vegas. You coulld fly out of Las Vegas if this is all the time you have, or you could then drive to LA and/or San Diego. Makes me want to go again, happy planning, ask away, I know this site is for Florida but I think several of us has done The West Coast and will be able to help.