This reminds me of an incident during my very first visit to the US in 1991. We had just arrived at Denver airport where we were met by resident relatives with whom we were staying. On the way to their house in Peublo, we stopped at a roadside diner for supper. After some time, still jetlagged, I went over to one of the staff and asked him where the loo was. He looked at me blankly and said 'She went home a couple of hours earlier'. It turned out that he had a female colleague named Lou(ise). After mutual explanations, he started laughing so hard that I thought he was going to bust a gut or something. He was still amused when we left half an hour later.