We did the drive last year and took the 27 down to Lake Wales then headed East on SR60 and picked up the Turnpike at the great sounding Yeehaw Junction.

Did the trip in under 8 hours with one short pit stop.

This route suited us as the villa we were in was on the 27 (High Grove).

Getting to Miami is no problem, it's the drive down the Keys that takes all the time!!