We have had both the 300C and the Highlander before. The 300C is a lovely comfortable car
and good for longer distances (although a little greedier on gas!). The 4 x 4 was very flexible with lots of space and as the others have mentioned , you get a good view from the high seats. The Highlander suited our needs very well. Three large suitcases easily fitted in the rear section without having to reposition seats.
Another option worth considering is the Chrysler Pacifica which we also loved. Up to six seats (or loads of space) and very comfortable to drive.